Publications

Watkins RA, King JS, Johnston SA. (2017) Nutritional Requirements and Their Importance for Virulence of Pathogenic Cryptococcus Species. Microorganisms. 2017 Sep 30;5(4). pii: E65. doi: 10.3390/microorganisms5040065.

Gilbert AS, Seoane PI, Sephton-Clark P, Bojarczuk A, Hotham R, Giurisato E, Sarhan AR, Hillen A, Velde GV, Gray NS, Alessi DR, Cunningham DL, Tournier C, Johnston SA, May RC. (2017) Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5. Sci Adv. 2017 Aug 16;3(8):e1700898. doi: 10.1126/sciadv.1700898

Evans RJ, Voelz K, Johnston SA, May RC. (2017) Using Flow Cytometry to Analyze Cryptococcus Infection of Macrophages. Methods Mol Biol. 2017;1519:349-357.

Farrer RA, Voelz K, Henk DA, Johnston SA, Fisher MC, May RC, Cuomo CA. (2016) Microevolutionary traits and comparative population genomics of the emerging pathogenic fungus Cryptococcus gattii. Philos Trans R Soc Lond B Biol Sci. 2016 Dec 5;371(1709). pii: 20160021. doi: 10.1098/rstb.2016.0021.

Dee CT, Nagaraju RT, Athanasiadis EI, Gray C, Fernandez Del Ama L, Johnston SA, Secombes CJ, Cvejic A, Hurlstone AF (2016) CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell-like Populations and Diverse Mononuclear Phagocytes. J Immunol. 2016 Nov 1;197(9):3520-3530. Epub 2016 Sep 30.

Buckley CM, Gopaldass N, Bosmani C, Johnston SA, Soldati T, Insall RH, King JS. (2016) WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5906-E5915. Epub 2016 Sep 19.

Bojarczuk A, Miller KA, Hotham R, Lewis A, Ogryzko NV,Kamuyango AA, Frost H, Gibson RH, Stillman E, May RC, RenshawSA and Johnston SA (2016) Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection. Scientific Reports 6:21489. doi: 10.1038/srep21489 

Johnston SA, Voelz K, May RC (2016) Cryptococcus neoformans Thermotolerance to Avian Body Temperature Is Sufficient For Extracellular Growth But Not Intracellular Survival In Macrophages. Scientific Reports 6:20977. doi: 10.1038/srep20977 *Corresponding author

Jubrail J, Morris P, Bewley MA, Stoneham S, Johnston SA, Foster SJ, Peden AA, Read RC, Marriott HM, Dockrell DH. (2015) Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages. Cell Microbiol. 2015 Aug 6. doi: 10.1111/cmi.12485.

Gibson JF & Johnston SA (2015) Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis. Fungal Genetics and Biology. May;78:76-86. doi: 10.1016/j.fgb.2014.11.006.

Voelz K, Johnston SA, Smith LM, Hall RA, Idnurm A & May RC (2014) 'Division of labour' in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak. Nat Commun, 5, 5194.

Sabiiti W, Robertson E, Beale MA, Johnston SA, Brouwer AE, Loyse A, Jarvis JN, Gilbert AS, Fisher MC, Harrison TS, May RC & Bicanic T (2014) Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis. Journal of Clinical Investigation, 124(5), 2000-2008.

Johnston SA & May RC (2013) Cryptococcus interactions with macrophages: Evasion and manipulation of the phagosome by a fungal pathogen. Cellular Microbiology, 15(3), 403-411.

Chayakulkeeree M, Johnston SA, Oei JB, Lev S, Williamson PR Wilson CF, Zuo X, Leal AL, Vainstein MH, Meyer W, Sorrell TC, May RC and Djordjevic JT (2011) SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans. Mol Microbiol. 2011 May;80(4):1088-101

Carnell M, Zech T, Calaminus S, Ura S, Hagedorn M, Johnston SA, May RC, Soldati T, Machesky LM and Insall RH (2011) Actin Polymerization Driven by WASH Causes V-ATPase Retrieval and Vesicle Neutralization Before Exocytosis. J Cell Biol. 2011 May 30;193(5):831-9.

Voelz K, Johnston SA, Rutherford JC, May RC (2010). Automated Analysis of Cryptococcal Macrophage Parasitism Using GFP-Tagged Cryptococci. PLoS One. 2010 Dec 31;5(12):e15968.

Johnston SA and May RC (2010). The Human Fungal Pathogen Cryptococcus neoformans Escapes Macrophages by a Phagosome Emptying Mechanism that is Inhibited by Arp2/3 Complex-Mediated Actin Polymerisation. PLoS Pathog. 2010 Aug 12;6(8). pii: e1001041.

Ma H, Hagen F, Stekel DJ, Johnston SA, Sionov E, Falk R, Polacheck I, Boekhout T, May RC (2009). The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation. Proc Natl Acad Sci U S A. Aug 4;106(31):12980-5

Johnston SA, Bramble JP, Yeung CL, Mendes PM, Machesky LM (2008). Arp2/3 complex activity on filopodia of spreading cells. BMC Cell Biol. Dec 9;9(1):65.

Machesky LM and Johnston SA (2007). MIM: a multifunctional scaffold protein. J Mol Med. 2007 Jun;85(6):569-76.

Legg JA, Bompard G, Dawson J, Morris HL, Andrew N, Cooper L, Johnston SA, Tramountanis G, Machesky LM (2007). N-WASP involvement in dorsal ruffle formation in mouse embryonic fibroblasts. Mol Biol Cell. 2007 Feb;18(2):678-87

 

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