MRC Fellow, Krebs Institute Fellow and Principal Investigator.
I did my PhD with Prof. Laura Machesky on the Arp2/3 complex and the actin cytoskeleton, and was a post-doc with Prof. Robin May working on host pathogen interactions of Cryptococcus. Now I am occasionally allowed in the lab to do microscopy, cell work and flow cytometry. To find out more about our research please see our research section.
I am very involved with gender equality through the Medical School Athena SWAN team and I represent the Faculty of Medicine on the University of Sheffield Gender Equality Committee. I am also passionate about public engagement in science and we have a number of past and ongoing projects in this area that can be seen here.
Aleks joined the Johnston lab in 2012 as a Research Assistant. Aleks previously worked in Steve Renshaw's lab screening for new drugs for inflammation resolution. This work led to this wonderful paper in Science Translational Medicine. Aleks has developed many of the methods and techniques we use in the lab including the high content imaging methods and is currently working on several projects concerning the disruption and activation of macrophages and neutrophils in cryptococcal infection. Aleks likes the colour blue, Lavazza ground coffee, classical music, red wine, jogging, cycling, singing, reading books. Absolutely afraid of fat spiders
Josie is an A* PhD student who is currently in Phil Ingham's lab at the IMCB in Singapore for two years as part of her PhD. Josie is working on differences in phagosome processing in zebrafish models of cryptococcosis and S. aureus infection.
Joe is a MPhil student co-supervised by Martin Bewley and David Dockrell. Joe is investigating the mechanisms of pneumolysin mediated membrane disruption.
Alfred is Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology PhD student. He joined the Johnston lab in 2014. Before joining the lab he did an MRes in Medical Mycology and Fungal Immunology where we worked on Aspergillus species and their interaction with chronic granulomatous disease phagocytes. His present PhD project is looking at interaction of C. neoformans with macrophages in zebrafish. He is funded by the Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology. Alfred likes photography and cycling. Don't take any notice of his photo, he is always smiling.
Hamid completed his Masters in Biomedical Engineering in 2012 from Amirkabir University of Technology. He joined the Johnston lab as a PhD student (joint with Alejandro Frangi in CISTIB) in January, 2015. He is currently working on the development of methods and tools for generating and analysing light microscopy data of host pathogen interactions in zebrafish, with the aim of generating three-dimensional light microscopy data sets that can be analysed automatically. Aleks will be very pleased when he has done this. Hamid was ranked third as an amateur rallying navigator.
Rhys is a BMedSci student (an intercalated research degree as part of Medical School) working on how Cryptococcus exploits immune dysfunction using the amoeba Dictyostelium discoideum. He aims to complete his BMedSci in 2016 and his medical degree in 2016. In longer term Rhys is interested in working as clinician in Immunology or Infectious Diseases and combining this with teaching or research. Rhys is a keen musician and has just started learning sign language.
Rory is new to the Johnston lab, joined the team alongside Rhys in August 2015. He is a BMedSci student, intercalating after his third year of a medical degree. During his year-long placement, Rory is researching the effect of mycophenolate on macrophage function and their ability to fight off cryptococcal infection. With interests in both infectious diseases and international health, Rory hopes to one day work in the international aid work field specialising in infectious diseases.
Aristeidis is Masters student in the Department of Biomedical Sciences. During his lab project Aristeidis is researching the regulation of vomocytosis in vivo.